Anti-VDAC1/Porin Rabbit Monoclonal Antibody

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

30773 MW

WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Voltage-dependent anion-selective channel protein 1

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Subcellular Markers, Tags & Cell Markers

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Boster Bio Anti-VDAC1/Porin Rabbit Monoclonal Antibody catalog # M01168. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.