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Anti-TTF1 (Thyroid transcription factor 1) NKX2-1 Rabbit Monoclonal Antibody, Clone#RM373

Anti-TTF1 (Thyroid transcription factor 1) NKX2-1 Rabbit Monoclonal Antibody, Clone#RM373

Item no.	BOS-M01322-2
Manufacturer	Boster
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Lung Cancer Bladder Cancer Thyroid Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Clone	RM373
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Homeobox protein Nkx-2.1;Homeobox protein NK-2 homolog A;Thyroid nuclear factor 1;Thyroid transcription factor 1;TTF-1;Thyroid-specific enhancer-binding protein;T/EBP;NKX2-1 ;NKX2A, TITF1, TTF1;
Available
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies, 2279
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	38596 MW
Clonality	Monoclonal
Application Details	Immunohistochemistry (IHC): 1:500-1:1000 dilution WB: 1:1000-1:20000 dilution.
Manufacturer - Gene Name	NKX2-1
Gene Full Name	Homeobox protein Nkx-2.1
Immunogen	A peptide corresponding to N-terminus of human TTF1 (Thyroid transcription factor 1) (Homeobox protein Nkx-2.1)
Contents	50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification	Protein A affinity purified from an animal origin-free culture supernatant
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Epigenetics and Nuclear Signaling, Transcription
Protein Function	Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).
Subcellular Localization	Nucleus.
Short Description	Boster Bio Anti-TTF1 (Thyroid transcription factor 1) NKX2-1 Rabbit Monoclonal Antibody, Clone#RM373 (Catalog # M01322-2). Tested in IHC, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-TTF1 (Thyroid transcription factor 1) NKX2-1 Rabbit Monoclonal Antibody, Clone#RM373 (Catalog # M01322-2). Tested in IHC, WB applications. This antibody reacts with Human.
Tissue Specificity	Thyroid and lung.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01322-2-datasheet.pdf

BOS-M01322-2-safety-datasheet.pdf