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Anti-Matrix metalloproteinase-12 (MMP-12) Rabbit Monoclonal Antibody, Clone#RM381 European Partner

Item no. BOS-M01520-1
Manufacturer Boster
Amount 100 ul
Category
Type Antibody Primary
Format Liquid
Applications WB, IHC
Clone RM381
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Macrophage metalloelastase;MME;3.4.24.65;Macrophage elastase;ME;hME;Matrix metalloproteinase-12;MMP-12;MMP12;HME;
Available
Manufacturer - Category
Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies, 2279
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
54002 MW
Clonality
Monoclonal
Application Details
Immunohistochemistry (IHC): 1:1000-1:2500 dilution

WB: 1:200-1:1000 dilution.
Manufacturer - Gene Name
MMP12
Gene Full Name
Macrophage metalloelastase
Immunogen
A peptide corresponding to C-terminus of human Matrix metalloproteinase-12 (MMP-12)
Contents
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Angiogenesis, Atherosclerosis, Cancer, Cardiovascular, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction, Tumor Biomarkers
Protein Function
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Subcellular Localization
Secreted, extracellular space, extracellular matrix.
Short Description
Boster Bio Anti-Matrix metalloproteinase-12 (MMP-12) Rabbit Monoclonal Antibody, Clone#RM381 (Catalog # M01520-1). Tested in IHC, WB applications. This antibody reacts with Human.
Description
Boster Bio Anti-Matrix metalloproteinase-12 (MMP-12) Rabbit Monoclonal Antibody, Clone#RM381 (Catalog # M01520-1). Tested in IHC, WB applications. This antibody reacts with Human.
Tissue Specificity
Found in alveolar macrophages but not in peripheral blood monocytes.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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