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Anti-Bim BCL2L11 Rabbit Monoclonal Antibody

Anti-Bim BCL2L11 Rabbit Monoclonal Antibody

Item no.	BOS-M01552
Manufacturer	Boster
Amount	100 ul
Quantity options	100 ul 30 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Autophagy Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, IF, IP, IHC, ICC
Clone	CBE-2
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Bcl-2-like protein 11,Bcl2-L-11,Bcl2-interacting mediator of cell death,BCL2L11,BIM
Available
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	65-80 kDa
Calculated Molecular weight	22171 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:1000 IHC 1:50-1:100 ICC/IF 1:50-1:100 IP 1:40 FC 1:50
Gene Name	BCL2L11
Gene Full Name	Bcl-2-like protein 11
Immunogen	A synthesized peptide derived from human Bim
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Alzheimer's Disease, Apoptosis, Apoptotic Markers, Associated Proteins, Cancer, Cell Biology, Cell Death, Immunology, Innate Immunity, Intracellular, Invasion/Microenvironment, Macrophage/Inflammation, MAPK Pathway, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
Subcellular Localization	Endomembrane system; Peripheral membrane protein. Associated with intracytoplasmic membranes.
Description	Boster Bio Anti-Bim BCL2L11 Rabbit Monoclonal Antibody catalog # M01552. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01552-datasheet.pdf

BOS-M01552-safety-datasheet.pdf