Anti-Myosin Light Chain 2 Rabbit Monoclonal Antibody

Rabbit Monoclonal Antibodies

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

18789 MW

WB 1:1000-1:5000
IHC 1:50-1:200
IP 1:50

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Motor Proteins, Myosin, Signal Transduction

Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).

Boster Bio Anti-Myosin Light Chain 2 Rabbit Monoclonal Antibody catalog # M03215. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.