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Anti-Phospho Girdin (Ser1417) CCDC88A Antibody

Anti-Phospho Girdin (Ser1417) CCDC88A Antibody

Item no.	BOS-P03282
Manufacturer	Boster
Amount	100 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Antibodies By Cell Type Immunohistochemistry Primary Antibodies Astrocytoma
Type	Antibody
Format	Liquid
Applications	IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CCDC88A;APE;GRDN;KIAA1212;Girdin;Akt phosphorylation enhancer;APE;Coiled-coil domain-containing protein 88A;G alpha-interacting vesicle-associated protein;GIV;Girders of actin filament;Hook-related protein 1;HkRP1
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	216042 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry, 1:100 - 1:300 ELISA, 1:5000 Not yet tested in other applications.
Manufacturer - Gene Name	CCDC88A
Gene Full Name	Girdin
Immunogen	A peptide derived from human Girdin around the phosphorylation site of Ser1417. Immunogen sequence location: 1383-1432
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cell Adhesion Proteins, Cytoskeleton, Cytoskeleton/ECM, Membrane Proteins, Microtubules, Neuroscience, Signal Transduction
Protein Function	Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
Subcellular Localization	Membrane. Cell membrane. Cytoplasm, cytosol. Cytoplasmic vesicle. Cell projection, lamellipodium. Localizes to the cell membrane through interaction with phosphoinositides.
Short Description	Boster Bio Anti-Phospho Girdin (Ser1417) CCDC88A Antibody (Catalog# P03282). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-Phospho Girdin (Ser1417) CCDC88A Antibody (Catalog# P03282). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Expressed ubiquitously.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-P03282-datasheet.pdf

BOS-P03282-safety-datasheet.pdf