Manufacturer |
Boster
|
Category |
|
Type |
Elisa-Kit |
Specific against |
Chicken |
Applications |
ELISA |
Amount |
96 wells/kit, with removable strips. |
Item no. |
BOS-EK1103-CH |
eClass 6.1 |
32160605 |
eClass 9.0 |
32160605 |
Available |
|
Alias |
Transforming growth factor beta-3;TGF-beta-3;Latency-associated peptide;LAP;TGFB3; |
Manufacturers Product Category |
PicoKine® ELISA Kits |
Manufacturers Research Category |
Angiogenesis, Cancer, Growth Factors, Growth Factors/Hormones, Invasion/Microenvironment, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, TGF Beta |
Short Description |
Chicken TGF-Beta 3 ELISA Kit PicoKine® (96 Tests). Quantitate Chicken TGFB3 in cell culture supernatants, serum, plasma (EDTA) and urine. Sensitivity: 10pg/ml. |
Description |
Chicken TGF-Beta 3 ELISA Kit PicoKine® (96 Tests). Quantitate Chicken TGFB3 in cell culture supernatants, serum, plasma (EDTA) and urine. Sensitivity: 10pg/ml. |
Background |
Transforming growth factor beta 3 (TGF-beta 3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGF-beta 3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-beta 3, mammals develop a deformity known as acleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse. TGF-beta 3 also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. TGF-beta 3 activated Lef1 in the absence of beta-catenin (CTNNB1) via nuclear phospho-Smad2 and Smad4. |
Gene Name |
TGFB3 |
Immunogen |
Expression system for standard: NS0; Immunogen sequence: A301-S412 |
Cross-reactivity |
There is no detectable cross-reactivity with other relevant proteins. |
Sample Type |
cell culture supernatants, serum, plasma (EDTA) and urine. |
Capture antibody|Detection antibody |
monoclonal antibody from mouse|polyclonal antibody from goat |
Storage |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
Anticoagulant |
EDTA |
Molecular Weight |
47328 MW |
Protein Function |
Involved in embryogenesis and cell differentiation. |
Subcellular Localization |
Secreted. |
Sequence Similarities |
Belongs to the TGF-beta family. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.