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BCAR1 Breast Cancer Anti-Estrogen Resistance 1 Human Recombinant Protein

BCAR1 Breast Cancer Anti-Estrogen Resistance 1 Human Recombinant Protein

Manufacturer	Boster
Category	Oncology Peptides & Proteins Recombinant Proteins By Organ Breast Cancer
Type	Proteins Recombinant
Specific against	other
Format	Solution
Amount	10ug
Item no.	BOS-PROTP56945
eClass 6.1	34160400
eClass 9.0	42020190
Available
Contents	The BCAR1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Description	BCAR1 Human Recombinant produced in E. coli is. a single polypeptide chain containing 407 amino acids (465-848) and having a molecular mass of 43.9kDa. BCAR1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Gene name	BCAR1
Protein function	Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Purification	Greater than 85% as determined by SDS-PAGE.
Shipping	Shipped with wet ice
Short description	BCAR43.9kDa. BCAR1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Storage	Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization	Cell junction, focal adhesion
Tissue specificity	Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line.
Format Information	Sterile Filtered clear solution.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10ug

available

Delivery expected until 5/30/2024