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WYC-209

WYC-209

Item no.	CS-0084453-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	2131803-90-0
Available
CAS	2131803-90-0
Purity	>98%
Formula	C20H20N2O3S
MWt	368.45
Solubility	H2O : < 0.1 mg/mL (insoluble); DMSO : 83.33 mg/mL (226.16 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease; Apoptosis
Target	RAR/RXR; Apoptosis
Biological Activity	WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. WYC-209 induces apoptosis primarily via the caspase 3 pathway (IC₅₀=0.19?uM for inmalignant murine melanoma TRCs), and has long-term effects with little toxicity^[1]. IC50 & Target: Retinoic acid receptor^[1] In Vitro: WYC-209 (10 uM; 24 hours) is able to inhibit and block growth of TRCs of human tumor cells in culture with a long-lasting effect^[1]. In Vivo: WYC-209 (0.022-0.22 mg/kg; i.v.; once every two days for 25 days) inhibits tumor metastasis in C57BL/6 mice bearing lung metastases^[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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