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LY450108

LY450108

Item no.	CS-1090-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	376594-67-1
Available
CAS	376594-67-1
Purity	>98%
Formula	C19H22F2N2O3S
MWt	396.45
Solubility	DMSO : >= 50 mg/mL (126.12 mM); H2O : < 0.1 mg/mL (insoluble)
Clinical Information	No Development Reported
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Target	iGluR; iGluR
Biological Activity	LY450108 is an alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor potentiator. IC50 value: Target: AMPA receptors mediate most of the excitatory neurotransmission and play a key role in synaptic plasticity in the mammalian central nervous system (CNS). Recent evidence has shown that in addition to modulating fast synaptic plasticity and memory processes, AMPA receptor potentiators alter downstream signalling pathways and may thereby have utility in other CNS disorders.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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