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AFN-1252

AFN-1252

Item no.	CS-4313-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	620175-39-5
Available
Alternative Names	API-1252; Debio 1452
CAS	620175-39-5
Purity	>98%
Formula	C22H21N3O3
MWt	375.42
Solubility	DMSO : 5.8 mg/mL (15.45 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Anti-infection
Target	Bacterial
Biological Activity	AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of <=0.12 ug/ml. IC50 value: Target: Antibiotic agent AFN-1252 was inactive (MIC90, >4 ug/ml) against clinical isolates of Streptococcus pneumoniae, beta-hemolytic streptococci, Enterococcus spp., Enterobacteriaceae, nonfermentative gram-negative bacilli, and Moraxella catarrhalis. These data support the continued development of AFN-1252 for the treatment of patients with resistant staphylococcal infections.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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