« Back
Home /
CBR-5884

CBR-5884

Item no.	CS-5648-25mg
Manufacturer	ChemScene
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	681159-27-3
Available
CAS	681159-27-3
Purity	>98%
Formula	C14H12N2O4S2
MWt	336.39
Solubility	H2O : < 0.1 mg/mL (insoluble); DMSO : 50 mg/mL (148.64 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC₅₀ of 33 uM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis^[1]. IC50 & Target: PHGDH, serine synthesis^[1] In Vitro: CBR-5884 (15 or 30 uM; 3-5 days) selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CS-5648-25mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 25mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 15 days

Compare

Add to wishlist

Get an offer