LRE1

Item no.	CS-0019660-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1252362-53-0
Similar products	1252362-53-0
Available
CAS	1252362-53-0
Purity	>98%
MWt	280.78
Formula	C12H13ClN4S
Solubility	DMSO : 125 mg/mL (445.19 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	GPCR/G Protein
Target	Adenylate Cyclase
Biological Activity	LRE1 is a specific and allosteric inhibitor of soluble adenylyl cyclase. IC50 & Target: Adenylyl cyclase^[1] In Vitro: LRE1 binds to the bicarbonate activator binding site and inhibits soluble adenylyl cyclase (sAC) via a unique allosteric mechanism^[1]. LRE1 prevents sAC-dependent processes in cellular and physiological systems and facilitates exploration of the therapeutic potential of sAC inhibition^[1]. LRE1 (0.5-100 uM, 60 minutes ) inhibits sperm and mitochondrial functions of sAC^[1].
Research Area	Cancer

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Amount: 100mg

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