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CDH1 / E Cadherin Antibody

CDH1 / E Cadherin Antibody

Item no.	ABC-ALS17189
Manufacturer	Abcepta
Amount	300 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	IHC-P
Specific against	other
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	E-Cadherin, CDH1, Cadherin-1, CAM 120/80, Epithelial cadherin, Uvomorulin, CD324, CDHE, UVO, Arc-1, ECAD, LCAM, CD324 antigen, Cell-CAM 120/80, E Cadherin
Available
Primary Accession	P12830
Application	IHC-P
Bio Background	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Bio References	Bussemakers M.J.G., et al.Mol. Biol. Rep. 17:123-128(1993). Oda T., et al.Proc. Natl. Acad. Sci. U.S.A. 91:1858-1862(1994). Rimm D.L., et al.Biochem. Biophys. Res. Commun. 200:1754-1761(1994). Ito K., et al.Oncogene 18:7080-7090(1999). Shibamoto S., et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Clonality	Polyclonal
Gene ID	999
Gene Name	CDH1
Subtitle	Goat Polyclonal Antibody
Reactivity	H, M, Rat, Pr, Dog
Legend image 1	Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Type image 1	IHC-P
Legend image 2	Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Type image 2	IHC-P
Legend image 3	Endogenous CDH1 detected with Anti-CDH1 Ab at 1:500 dilution. Lysate at 100ug per lane.
Type image 3	WB
Calculated MW	97456
Target/Specificity	Detects endogenous levels of total E-cadherin protein by Western blot in the whole cell lysates (e.g. HeLa and COS-7). This Ab does not recognize CDH2.
Purification	Immunoaffinity purified
Concentration (mg/ml)	3 mg/ml
Reconstitution & Storage	PBS, 20% glycerol, 0.05% sodium azide. Store at 4°C for one month or -20°C for longer. Avoid freeze/thaw cycles.
Dilution	IHC-P (5 µg/ml),

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 300 ug

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Delivery expected until 10/2/2025

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