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alpha Tubulin [B-5-1-2]

alpha Tubulin [B-5-1-2]

Item no.	20-272-190439
Manufacturer	GENWAY
Amount	0.1 ml
Category	Oncology Antibodies Cell Biology Cytoskeleton Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Immunoassay Primary Antibodies Mikrotubules By Organ Lung Cancer
Type	Antibody
Applications	WB, IF, IP, ICC, RIA
Clone	B-5-1-2
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-75FBD1
Similar products	20-272-190439
Available
Genway ID:	GWB-75FBD1
Clone:	B-5-1-2
Isotype:	IgG1
Immunogen:	Sarkosyl-resistant filaments from Stronglycentrotus purpuratus (sea urchin).
Positive Control:	Total cell extract of the human foreskin fibroblast cell line (FS11)
Target:	alpha Tubulin
Localization:	Major constituent of microtubules.
Concentration:	2. 3 mg/ml Storage
Preservative:	15mM Sodium Azide; Constituents: 0. 01M PBS. pH 7. 4
Application Note:	ICC: Use at a concentration of 0. 5 - 1 µ g/ml this concentration is recommended using cultured chicken fibroblasts (CFB). IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. WB: Use at a concentration of 0. 25 - 0. 5 µ g/ml this concentration is recommended using a total cell extract of the human foreskin fibroblast cell line (FS11). Predicted
Molecular Weight:	50 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:	Major constituent of microtubules. Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis intracellular transport flagellar movement and in the cytoskeleton. Tubulin is a heterodimer which consists of alpha tubulin and beta tubulin.
Function:	Tubulin is the major constituent of microtubules. It binds two moles of GTP one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Subunit:	Dimer of alpha and beta chains.
Tissue Specificity:	Ubiquitously expressed although primarily in lung and brain.
Ptm:	Undergoes a tyrosination/detyrosination cycle the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL) respectively (By similarity).
Similarity:	Belongs to the tubulin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 ml

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Delivery expected until 9/25/2025

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