DMA

Item no.	CS-1309-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	188860-26-6
Available
CAS	188860-26-6
Purity	>98%
Formula	C27H28N6O2
MWt	468.55
Solubility	DMSO : >= 54 mg/mL (115.25 mM)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	DMA is a fluorescent compound (lambda_ex=340 nm, lambda_em=478 nm). IC50 & Target: IC50: 3.4 uM (HeLa cell), 5.3 uM (MCF7 cell)^[1] In Vitro: The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87) in comparison to Hoechst. In case of MCF7, the IC₅₀ is observed at 5.3 uM for DMA. The IC₅₀ determined in the case of HeLa is 3.4 uM for DMA^[1].

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