Cyproconazole

94361-06-5

C15H18ClN3O

DMSO : >= 34 mg/mL (116.53 mM)

Anti-infection

Cyproconazole is a triazole fungicide that is used agriculturally for protection of crops against a wide variety of fungal pathogens. In vitro: Cyproconazole has been shown to cause a dose dependent inhibition of progesterone production in human placental cells in vitro. cyproconazole exhibited the lowest capacity to increase CYP1A1 and were not able to activate the AhR in the transactivation assay. [1] In vivo: Cyproconazole, a triazole fungicide, causes hepatocellular adenomas and carcinomas in CD-1 mice at dose levels of 100 and 200 ppm. In wild-type mice, 200 ppm cyproconazole caused liver hypertrophy, increased liver weight and cell proliferation, single-cell necrosis and fat vacuolation. [2]