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Phospho-ERN1 (S724) Recombinant Monoclonal Antibody

Phospho-ERN1 (S724) Recombinant Monoclonal Antibody

Item no.	CSB-RA007795A724phHU-50ul
Manufacturer	Cusabio
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ELISA
Clone	1F12
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, hIRE1p, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, ERN1
Similar products	Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Ire1-alpha, Serine/threonine-protein kinase, Endoribonuclease, ERN1, IRE1a, hIRE1p
Available
Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	ERN1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide derived from human Phospho-ERN1 (S724)
Dilution	WB:1:500-1:5000, IF:1:20-1:200
Background	Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation (PubMed:9637683, PubMed:11175748, PubMed:12637535). The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis (PubMed:24508390).
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Signal Transduction
Modified	Signal Transduction
Antigen Species	Human
Antigen	A synthesized peptide derived from human Phospho-ERN1 (S724)
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 8/28/2025

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