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Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1)

Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1)

Item no.	CDE-M532-10mg
Manufacturer	ACROBiosystems
Amount	500 ug x 20
Quantity options	500 ug x 200 100 ug 500 ug x 20 500 ug x 2
Category	Peptides & Proteins Recombinant Proteins Flow Cytometry ELISA Immunostaining
Type	Proteins Recombinant
Format	Solid
Applications	FC, ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ELISA (Evaluation of levels of CD3 protein).Flow Cytometry (Detection the expression of CD3 on Human cells).
Manufacturer - Category	Antibody / Recombinant Antibodies
Manufacturer - Conjugate / Tag	Mouse IgG1 \| Mouse Kappa, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Manufacturer - Format	Powder
Description	Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1) is a monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.
Background	CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
Molecule	CD3
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower._x000D_Please avoid repeated freeze-thaw cycles.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CDE-M532-10mg-datasheet.pdf

CDE-M532-10mg-safety-datasheet.pdf