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PARP1 Antibody

PARP1 Antibody

Item no.	PRS-13-003-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Neuroscience Molecular Targets for Neuroscience Immunohistochemistry Cell Lines & Cell Culture Tissues
Type	Slides
Format	Liquid
Applications	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	PARP1
ECLASS 10.1	32160905
ECLASS 11.0	32160905
UNSPSC	41121800
Alias	KIF3B,PARP,PPOL,ADPRT,ARTD1,ADPRT1,PARP-1,ADPRT 1,pADPRT-1
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 116kDa
Manufacturer - Research Area	Cell Cycle, Immunology, Signal Transduction
Background	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
By Type	Cell Cycle, Immunology, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	Jurkat
Positive Control 2	HeLa
Positive Control 3	RAW264.7
Positive Control 4	C6
Positive Control 5	Mouse testis
Positive Control 6	Mouse brain
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:1000 - 1:2000 IF: 1:50 - 1:200
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 150-250 of human PARP1 (NP_001609.2).
Clonality	Polyclonal
NCBI Official Name	poly (ADP-ribose) polymerase 1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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