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Mouse Anti-Human VEGFR-2/KDR Clone 4 (20I6) mAb

Mouse Anti-Human VEGFR-2/KDR Clone 4 (20I6) mAb

Manufacturer	Cell Sciences
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Adenocarcinoma Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Bladder Cancer
Type	Antibody Monoclonal
Specific against	Human
Clone	4(20I6)
Isotype	IgG1
Applications	WB, FC, IHC, ELISA
Amount	100 ug
Host	Mouse
Item no.	CS-CMV016
Targets	VEGFA, KDR
eClass 6.1	32160702
eClass 9.0	42030590
Available
Application Notes	Western Blot: Use at 2-5 ug/mlFACS: Use at 2-5 ug/mlIF/IHC: Use at 6-30 ug/mlELISA: Use at 1-10 ug/ml The optimal concentration should be determined by the user for each specific application.
Description	VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Formulation	Lyophilized in PBS
Immunogen	Recombinant human soluble KDR (D7)
Purification	Protein G chromatography
Reconstitution	Centrifuge vial prior to opening. Add sterile distilled water to the vial to fully solubilize the antibody to a concentration of 0.1 to 1.0 mg/ml.
Storage and Stability	The lyophilized product, though stable at room temperature for three weeks, is best stored desiccated at -20C to -80C. Reconstituted protein is stable for two weeks at +2C to +4C, or for longer storage at -20C to -80C. Store in working aliquots. Avoid repeated freeze-thaw cycles.
Specificity	The antibody will detect native human VEGFR-2/KDR in ELISA and on the surface of different human cell types.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CMV016.pdf

CS-CMV016-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/30/2024