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Rabbit Anti-Mouse DFF40 Affinity Purified pAb

Rabbit Anti-Mouse DFF40 Affinity Purified pAb

Manufacturer	Cell Sciences
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Mouse
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	CS-CPD101
eClass 6.1	32160702
eClass 9.0	32160702
Available
Application Notes	Western blotting (0.5-4 ug/ml) and Immunohistochemistry (2-8 ug/ml). However, the optimal conditions should be determined individually. The antibody detects a 43 kDa DFF40/CAD of human, mouse and rat origins. Mouse kidney tissue lysate can be used as a positive control.
Concentration	0.2 mg/ml
Cross-Reactivity	Human, mouse, and rat
Description	Rabbit Anti-Multispecies DFF40 Affinity Purified polyclonal antibody. DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase 3, leads to DFF40’s activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary.
Formulation	Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide surrounding amino acid 208 of mouse DFF40
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Specificity	The antibody detects a 43 kDa DFF40/CAD of human, mouse and rat origins. Mouse kidney tissue lysate can be used as a positive control.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CS-CPD101-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/23/2024