Human IL-6 PeliKine Compact ELISA Kit

Interleukin 6 (IL-6) is a mediator of the inflammatory response and is involved in the induction of acute phaseproteins and the development of fever. A marked correlation between IL-6 levels and inflammatory processeshas been demonstrated in synovial fluid and serum of rheumatoid arthritis patients and in serum of patientswith burns. It was demonstrated that in recipients of kidney transplants the IL-6 levels in serum and urinehallmark the onset of rejection episodes. Elevated IL-6 levels were also observed in sera of patients withseptic shock, multiple myeloma and alcoholic hepatitis, and a significant difference between IL-6 levels ofsurvivors and non-survivors was found.Bioassays for the quantification of IL-6, based on the proliferation of B-cell hybridomas have been used forseveral years. These assays, although sensitive, are time consuming and susceptible to interference by othersubstances.This PeliKine compact™ IL-6 ELISA kit has been developed for faster, more reproducible and specificquantification of human IL-6 (huIL-6) in plasma and other body fluids, as well as in cell-culture supernatant.