Recombinant Human GRK5 GST Active

Store product at -80C. When stored at -80C product is stable for one year from date of shipment. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

Recombinant human full length GRK5 Active containing N-terminal GST tag. GRK5 is a member of the guanine nucleotide-binding protein (G-protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. GRK5 plays a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Densensitization of G protein-coupled receptors regulates the number of polymorphonuclear leukocytes (PMNs), as well as their motility and ability to stop upon contact with pathogens or target cells, and this desensitization is mediated by GRK5.

33 nmol/min/mg