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Recombinant Human PDGF-BB

Recombinant Human PDGF-BB

Item no.	CS-CRP302C
Manufacturer	Cell Sciences
Amount	1.0 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis By Cell Type Blastoma Carcinoma Glioma Sarcoma Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	>95.0% as determined by reducing and non-reducing SDS-PAGE and UV spectroscopy at 280 nm
Sequence	SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIGIVRK KPIFKKATVT LGDHLACKCE TVAAARPVT
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	PDGF, PDGF2, SIS, Platelet-derived growth factor, B chain, FLJ12858, SSV, c-sis, beta polypeptide (oncogene SIS), becaplermin, platelet-derived growth factor 2, platelet-derived growth factor beta, oncogene SIS, platelet-derived growth factor, v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)
Available
Manufacturer - Category	Biomolecules
Storage Conditions	Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Molecular Weight	ca.24.3 kDa.
Description	Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF. Recombinant Human PDGF-BB is a non-glycosylated, disulfide-linked homodimer containing two 109 amino acid chains.
Formulation	Recombinant human PDGF-AA is lyophilized from 10 mM acetic acid (AcOH).
Reconstitution	Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Biological Activity	The activity is determined by the dose-dependent proliferation of 3T3 indicator cells and is typically 1.5-2.2 ng/ml.
Endotoxin Level	Measured by kinetic LAL analysis and is typically <=1 EU/ug protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CS-CRP302C-datasheet.pdf

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Amount: 1.0 mg

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Delivery expected until 8/14/2025

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