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Recombinant Human TNFR1

Recombinant Human TNFR1

Item no.	CS-CRT104B
Manufacturer	Cell Sciences
Amount	20 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	UV spectroscopy at 280 nm. RP-HPLC calibrated against a known standard. Quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
Sequence	MDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESSGSF TASENHLRHC LSCSKCRKEM GQVEKSSCTV DRDTVCGCRK NQYRHYWSEN LFQCFNCSLC LNGTVHLSCQ EKQNTVCTCH AGFFLRENEC VSCSNCKKSL ECTKLCLPQI EN
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	TNF-R1, TNFR1, p55, TNFAR, p60, TNF-RI, TNFR-I, CD120a, TBP1, FPF, MGC19588, TNF-R, TNF-R-I, TNF-R55, TNFR55, TNFR60, p55-R, tumor necrosis factor binding protein 1, tumor necrosis factor receptor 1, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor-alpha receptor, tumor necrosis factor receptor type 1, tumor necrosis factor receptor type I, tumor necrosis factor receptor 1A isoform beta
Available
Manufacturer - Category	Biomolecules
Storage Conditions	Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
Molecular Weight	20.9 kDa
Description	TNF Receptor I (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound TNF-a. TNFR1 is known to activate NF-eB and MAPK pathways and functions to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis and inhibit viral replication. The soluble form of human recombinant TNFR1 is a non-glycosylated protein, containing 192 amino acids and having a MW = 20.9 kDa.
Formulation	Recombinant human TNFR1 is lyophilized from 10 mM Na2PO4, pH 7.5.
Reconstitution	Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Biological Activity	The activity is determined by its ability to inhibit the cytolytic effects 0.25 ng/mL TNFa has on mouse L929 cells, in the presence of Actinomycin D, and is typically between 0.045 and 0.09 ng/mL.
Endotoxin Level	Endotoxin level, as measured by LAL analysis, is <0.01ng/ug or <0.1EU/ug.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 8/14/2025

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