Comparison

Recombinant Mouse PDGF-BB

Item no. CS-CRP138A
Manufacturer Cell Sciences
Amount 2 ug
Category
Type Proteins
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Purity Greater than 98% as determined by reducing and non-reducing SDS-PAGE, UV spectroscopy at 280 nm
Sequence MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products PDGF-BB, PDGF2, SIS, Platelet-derived growth factor beta polypeptide, FLJ12858, SSV, c-sis, Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF B-chain, Becaplermin.
Available
Storage Conditions
Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Molecular Weight
24.6 kDa
Description
Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF. Recombinant mouse PDGF-BB is a non-glycosylated, disulfide-linked homodimer, containing two 109 amino acids chains
Formulation
Recombinant mouse PDGF-BB is lyophilized from 10 mM sodium citrate, pH 3.0.
Reconstitution
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Biological Activity
Fully biologically active when compared to standard. The activity as measured by the dose-dependent proliferation in mouse 3T3 fibroblasts is 0.2-0.3 ng/ml.
Endotoxin Level
Measured by kinetic LAL analysis and is typically <= 1 EU/ug protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2 ug
Available: In stock
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