Comparison

Recombinant Mouse Soluble RANK Ligand

Item no. CS-CRR101B
Manufacturer Cell Sciences
Amount 10 ug
Category
Type Proteins
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Purity 95% by reducing and non-reducing SDS-PAGE and UV spectroscopy at 280 nm.
Sequence PAMMEGSWLD VAQRGKPEAQ PFAHLTINAA SIPSGSHKVT LSSWYHDRGW AKISNMTLSN GKLRVNQDGF YYLYANICFR HHETSGSVPT DYLQLMVYVV KTSIKIPSSH NLMKGGSTKN WSGNSEFHFY SINVGGFFKL RAGEEISIQV SNPSLLDPDQ DATYFGAFKV QDID
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products CD254, RANKL, ODF, OPGL, OPTB2, TRANCE, hRANKL2, sOdf, OTTHUMP00000178585, TNF-related activation-induced cytokine, osteoclast differentiation factor, osteoprotegerin ligand, receptor activator of nuclear factor kappa B ligand, RP11-86N24.2, tumor necrosis factor ligand superfamily member 11, receptor activator of nuclear factor kappa-B ligand
Available
Manufacturer - Category
Biomolecules
Storage Conditions
Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Molecular Weight
19.9 kDa
Description
Receptor Activator of NF-kappaB Ligand (RANK Ligand) is a cell-bound marker (CD254) related to the TNF family of proteins. RANK Ligand plays a critical role in bone metabolism, particularly osteoclast differentiation. In addition, RANK Ligand is expressed by some T cells is thought to promote dendritic cell maturation. Recombinant mouse soluble RANK Ligand is a non-glycosylated protein, containing 174 amino acids.
Formulation
Sterile filtered and lyophilized from 10 mM Na2PO4, pH 7.5 + 50 mM NaCl.
Reconstitution
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Biological Activity
Measured by its ability to induce osteoclast formation in RAW264.7 cells using a concentration of 50 ng/ml.
Endotoxin Level
0.22 EU/ug protein (with a 50% confidence range)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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