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MDA-MB-231 cells

MDA-MB-231 cells

Item no.	C0006002
Manufacturer	Addexbio
Amount	One Frozen vial
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Cell Lines & Cell Culture Cell Lines By Organ Lung Cancer Skin Cancer Breast Cancer
Type	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Altenburg, J. D. and Siddiqui, R. A. Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells. Mol Cancer Res, 7: 1013-1020, 2009. 2.Aroui, S., Brahim, S., De Waard, M., Breard, J., and Kenani, A. Efficient induction of apoptosis by doxorubicin coupled to cell-penetrating peptides compared to unconjugated doxorubicin in the human breast cancer cell line MDA-MB 231. Cancer Lett, 285: 28-38, 2009. 3.Aroui, S., Brahim, S., Hamelin, J., De Waard, M., Breard, J., and Kenani, A. Conjugation of doxorubicin to cell penetrating peptides sensitizes human breast MDA-MB 231 cancer cells to endogenous TRAIL-induced apoptosis. Apoptosis, 14: 1352-1365, 2009. 4.Hunakova, L., Sedlakova, O., Cholujova, D., Gronesova, P., Duraj, J., and Sedlak, J. Modulation of markers associated with aggressive phenotype in MDA-MB-231 breast carcinoma cells by sulforaphane. Neoplasma, 56: 548-556, 2009. 5.Liu, Q., Loo, W. T., Sze, S. C., and Tong, Y. Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription. Phytomedicine, 16: 916-922, 2009. 6.Nakajima, S., Niizeki, H., Tada, M., Nakagawa, K., Kondo, S., Okada, F., and Kobayashi, M. Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231. Oncol Rep, 22: 143-148, 2009. 7.Naviglio, S., Di Gesto, D., Romano, M., Sorrentino, A., Illiano, F., Sorvillo, L., Abbruzzese, A., Marra, M., Caraglia, M., Chiosi, E., Spina, A., and Illiano, G. Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells. Cancer Biol Ther, 8: 1183-1190, 2009. 8.Phromnoi, K., Yodkeeree, S., Anuchapreeda, S., and Limtrakul, P. Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids. Acta Pharmacol Sin, 30: 1169-1176, 2009. 9.Wang, L., Liu, L. H., Shan, B. E., Zhang, C., Sang, M. X., and Li, J. [Celecoxib promotes apoptosis of breast cancer cell line MDA-MB-231 through down-regulation of the NF-kappaB pathway]. Ai Zheng, 28: 569-574, 2009.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
Available
Description	Disease: Breast adenocarcinoma Origin: Isolated from pleural effusions of a breast cancer patient Species: Homo sapiens Tissue: Breast, mammary gland Morphology: Epithelial Properties: Adherent Cytogenic data: Aneuploid female with chromosome counts in the near-triploid range Patient: Female, Caucasian, 51 yrs of age Medium: AddexBio-formulated Leibovitz's L-15 Medium (C0006-01) + 10% FBS Subculture: 1:2 to 1:4 (80-90%) using 0.25% trypsin or trypsin/EDTA, without CO2 (or use a non-vented flask and keep the lid closed); 37C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Protein Expression: Epidermal growth factor (EGF); transforming growth factor alpha (TGF alpha) Isoenzymes: Me-2, 1-2; PGM3, 1; PGM1, 1-2; ES-D, 1; AK-1, 1; GLO-1, 2; G6PD B DNA Profile (STR): Amelogenin: X, X CSF1PO:12, 13 D13S317:13 D16S539:12 D5S818:12 D7S820:8, 9 TH01:7, 9.3 TPOX:8, 9 vWA:15, 19 Citation Format: If use of this culture results in a scientific publication, it should be cited in the publication as: MDA-MB-231 (AddexBio C0006002) Mutations in MDA-MB-231 Cells Related cells by Organ: 4T1 AU-565 BT-20 BT-474 BT-483 BT-549 JIMT-1 MCF-7 SK-BR-3 T47D ZR-75-1
Storage condition	LN2
Manufacturers Category	Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: One Frozen vial

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