Comparison

AG014699

Item no. CT-AG01-50
Manufacturer ChemieTek
CASRN 459868-92-9
Amount 50 mg
Quantity options 10 mg 100 mg 200 mg 5 mg 50 mg
Category
Type Inhibitors
Specific against other
Purity 99.5% (HPLC)
Citations 1. Wang, Y. Frederick, Drugs of the Future (2009), 34(3), 177-182.
2. P. Plummer et al. Clin Cancer Res. 2008, 14(23), 7917-23
3. M. Ali et al. Clin. Cancer Res. 2009, 15(19), 6106-6112.
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias PF-01367338,Rucaparib
Available
Storage Conditions
Store at 0°C (short term), -20°C (long term), desiccated
Brief Description
AG014699 is a selective PARP1 inhibitor (Ki = 1.4 nM) with potential antineoplastic activity. It selectively binds to PARP 1 and inhibits the PARP1-mediated DNA repair, thus potentiating the genomic instability and apoptosis
Original QC Data
HPLC-MS, 1HNMR, and Quantitative Elemental Analysis
Solubility
In DMSO, water with 1 eq of acid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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