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BI 6727

BI 6727

Item no.	CT-BI6727-10
Manufacturer	ChemieTek
CASRN	755038-65-4
Amount	10 mg
Quantity options	10 mg 100 mg 200 mg 5 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99% (HPLC at 214 and 254 nm), >99% optical purity (Chiral HPLC referenced to opposite enantiomer)
Citations	1. Rudolph, D., et al, BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity, Clin Cancer Res., May 1, 2009; 15 (9), 3094-3102 2. K. Strebhardt, Nature Reviews Drug Discovery, 9, 643-660 (August 2010)
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Volasertib
Available
Storage Conditions	Store at 0°C (short term), -20°C (long term), desiccated
Brief Description	A highly potent, selective and ATP-competitive inhibitor of polo-like kinases 1 , 2 and 3 (PLK1, 2 and 3), with IC50s at 0.87, 5 and 56 nM, respectively.
Original QC Data	HPLC-MS, ¹HNMR and Quantitative Elemental Analysis
Solubility	In DMSO, alcohols, water with 2 eq. of acid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 9/4/2025

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