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LEE-011

LEE-011

Item no.	CT-LEE011-10
Manufacturer	ChemieTek
CASRN	1211441-98-3
Amount	10 mg
Quantity options	10 mg 100 mg 200 mg 50 mg 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	≥99.5% (HPLC, detected at 214 and 254 nm)
Citations	1. Rader J, et al. Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma. Clin Cancer Res. 2013 Oct 28.
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Storage Conditions	Store at 0°C (short term), -20°C (long term), desiccated
Brief Description	LEE-011 is an orally bioavailable, potent and highly selective (most selective CDK4/6 inhibitor to date) cyclindependent kinase 4 and 6 (CDK 4/6) with IC50 at low nM, currently in clinical trials.
Original QC Data	HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis
Solubility	Soluble in DMSO, and water with 2.0 eq. of HCl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 9/4/2025

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