Comparison

HIV (HIV1-HXB2) Capsid protein p24, His Tag (MALS verified) European Partner

Item no. CP4-H52H3-1mg
Manufacturer ACROBiosystems
Amount 1 mg
Quantity options 100 ug 1 mg
Category
Type Proteins Recombinant
Format Solid
Specific against Human Immunodeficiency Virus (HIV)
Host HEK293
Conjugate/Tag Unconjugated, HIS
Purity 90%
Formula PBS, pH7.4
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping Condition Room temperature
Available
Specificity HIV (HV1-HXB2)
Manufacturer - Category
Protein / Others
Manufacturer - Conjugate / Tag
C-10xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
27.5 kDa
Manufacturer - Format
Powder
Description
HIV (HIV1-HXB2) Capsid protein p24, His Tag (CP4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Pro 133 - Leu 363 (Accession # P04591).
Background
The Gag protein from retroviruses, also known as p24, forms the inner protein layer of the nucleocapsid. It is composed of two domains, the N-terminal domain (NTD), which contributes to viral core formation, and the C-terminal domain (CTD), which is required for capsid dimerisation, Gag oligomerization and viral formation. This protein performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA.
Molecule
Capsid protein p24/Gag p24 (HIV)
Exp Region
Pro 133 - Leu 363
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.5 kDa. The protein migrates as 26-27 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
available

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