Comparison

Rabbit anti-human ATP-sensitive inward rectifier potassium channel 10 polyclonal Antibody,FITC conjugated

Item no. CSB-PA012048LC01HU
Manufacturer Cusabio
Amount 100ug
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ATP-dependent inwardly rectifying potassium channel Kir4.1,Inward rectifier K(+) channel Kir1.2,Potassium channel, inwardly rectifying subfamily J member 10,KCNJ10
Available
Uniprot ID
P78508
Immunogen
Recombinant human ATP-sensitive inward rectifier potassium channel 10 protein(165-379aa?
Conjugate
FITC conjugated
Alias
ATP-dependent inwardly rectifying potassium channel Kir4.1, Inward rectifier K(+) channel Kir1.2, Potassium channel, inwardly rectifying subfamily J member 10, KCNJ10
Relevance
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
Buffer
Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Stroage
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
References
"Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10." Scholl U.I., Choi M., Liu T., Ramaekers V.T., Hausler M.G., Grimmer J., Tobe S.W., Farhi A., Nelson-Williams C., Lifton R.P. Proc. Natl. Acad. Sci. U.S.A. 106:5842-5847(2009).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
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