Item no. |
CSB-PA015878LC01HU |
Manufacturer |
Cusabio
|
Amount |
100ug |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
ELISA |
Specific against |
Human (Homo sapiens) |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
NLR family member X1,Caterpiller protein 11.3,CLR11.3,Nucleotide-binding oligomerization domain protein 26,Nucleotide-binding oligomerization domain protein 5,Nucleotide-binding oligomerization domain protein 9,NLRX1,NOD26,NOD5,NOD9 |
Available |
|
Background |
Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313). |
Alias |
NLR family member X1, Caterpiller protein 11.3, CLR11.3, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9, NLRX1, NOD26, NOD5, NOD9 |
Uniprot |
Q86UT6 |
Immuongen |
Recombinant Human NLR family member X1 protein (45-205AA) |
Counjugation |
FITC |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purification |
>95%, Protein G purified |
Abbreviation |
NLR family member X1 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.