Comparison

USP5 Antibody,Biotin conjugated

Item no. CSB-PA025742LD01HU
Manufacturer Cusabio
Amount 100ug
Category
Type Antibody Polyclonal
Format Liquid
Applications ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ubiquitin carboxyl-terminal hydrolase 5,Deubiquitinating enzyme 5,Isopeptidase T,Ubiquitin thioesterase 5,Ubiquitin-specific-processing protease 5,USP5,ISOT
Available
Background
Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Alias
Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, USP5, ISOT
Uniprot
P45974
Immuongen
Recombinant human Ubiquitin carboxyl-terminal hydrolase 5 protein (201-500AA)
Counjugation
Biotin
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Purification
>95%, Protein G purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
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