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Rabbit anti-human Complement factor B polyclonal Antibody,HRP conjugated

Rabbit anti-human Complement factor B polyclonal Antibody,HRP conjugated

Item no.	CSB-PA11049B0Rb
Manufacturer	Cusabio
Amount	100ug
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C3/C5 convertase,Glycine-rich beta glycoprotein,GBG,PBF2,Properdin factor B,CFB,BF, BFD
Available
Uniprot ID	P00751
Immunogen	Recombinant human Complement factor B protein
Conjugate	HRP conjugated
Alias	C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, CFB, BF, BFD
Relevance	Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Buffer	Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Stroage	Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Purity	Caprylic Acid Ammonium Sulfate Precipitation purified
Research Area	Others
References	"Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome."Maga T.K., Nishimura C.J., Weaver A.E., Frees K.L., Smith R.J.H.Hum. Mutat. 31:E1445-E1460(2010).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/11/2025

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