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WNK1 Antibody,FITC conjugated

WNK1 Antibody,FITC conjugated

Item no.	CSB-PA887978LC01HU
Manufacturer	Cusabio
Amount	100ug
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase WNK1,Erythrocyte 65 kDa protein,p65,Kinase deficient protein,Protein kinase lysine-deficient 1,Protein kinase with no lysine 1,hWNK1,WNK1,HSN2,KDP,KIAA0344,PRKWNK1
Available
Background	Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition (By similarity).
Alias	Serine/threonine-protein kinase WNK1, Erythrocyte 65 kDa protein, p65, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, hWNK1, WNK1, HSN2, KDP, KIAA0344, PRKWNK1
Uniprot	Q9H4A3
Immuongen	Recombinant Human Serine/threonine-protein kinase WNK1 protein (1-207AA)
Counjugation	FITC
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Purification	>95%, Protein G purified
Abbreviation	Serine/threonine-protein kinase WNK1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/4/2025

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