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RBBP6 Antibody

RBBP6 Antibody

Item no.	CSB-PA768776LA01HU
Manufacturer	Cusabio
Amount	100ug
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase RBBP6,Proliferation potential-related protein,Protein P2P-R,Retinoblastoma-binding Q protein 1,RBQ-1,Retinoblastoma-binding protein 6,p53-associated cellular protein of testis,RBBP6,P2PR,PACT,RBQ1,My038
Available
Background	E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites (CFSs) in a ZBTB38- and MCM10-dependent manner. Controls ZBTB38 protein stability and abundance via ubiquitination and proteasomal degradation, and ZBTB38 in turn negatively regulates the expression of MCM10 which plays an important role in DNA-replication (PubMed:24726359).
Alias	E3 ubiquitin-protein ligase RBBP6, Proliferation potential-related protein, Protein P2P-R, Retinoblastoma-binding Q protein 1, RBQ-1, Retinoblastoma-binding protein 6, p53-associated cellular protein of testis, RBBP6, P2PR, PACT, RBQ1, My038
Uniprot	Q7Z6E9
Immuongen	Recombinant Human E3 ubiquitin-protein ligase RBBP6 protein (351-97AA)
Counjugation	Non-conjugated
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage	Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Purification	>95%, Protein G purified
Abbreviation	E3 ubiquitin-protein ligase RBBP6

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 6/5/2025

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