Rabbit anti-human HNF1B polyclonal antibody

HNF1 homeobox B

Synthetic peptide of human HNF1B

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification