Comparison

Rabbit anti-human GRK1 polyclonal antibody

Item no. CSB-PA909936
Manufacturer Cusabio
Amount 100ul
Category
Type Antibody Polyclonal
Format liquid
Applications IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias G protein-coupled receptor kinase 1
Available
Alias
G protein-coupled receptor kinase 1
Uniprot ID
Q15835
Immunogen
Synthetic peptide of human GRK1
Tested applications
ELISA: 1:2000-1:5000; IHC: 1:50-1:200
Background
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
Conjugate
Non-conjugated
Stroage Buffer
-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Stroage
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Purity
Antigen affinity purification

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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