Comparison

Recombinant Human Interleukin-31 protein(IL31) (Active)

Item no. CSB-AP001901HU-2
Manufacturer Cusabio
Amount 2 ug
Quantity options 1 mg 10 ug 100 ug 2 ug 250 ug 500 ug
Category
Type Proteins Recombinant
Format Solid
Specific against other
Host E.coli
Conjugate/Tag Tag Free
Purity >97% as determined by SDS-PAGE and HPLC.
Sequence SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KD VEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPA IRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDA PETN ISVPTDTHEC KRFILTISQQ FSECMDLA LK SLTSGAQQAT T
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL-31,
Available
Manufacturer - Category
Cytokine / Interleukin
Molecular Weight
15.8 kDa
Buffer
0.2 um filtered PBS, pH7.4 , lyophilized
General Research Areas
Immunology
Relevance
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. {ECO:0000269|PubMed:15184896}.
Expression Region
24-164aa
Function
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR
Subcellular Location
Secreted
Tissue Specificity
Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
Gene Names
IL31
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Biological activity
Fully biologically active when compared to standard. The specific activity is determined by inducing STAT3 activation using human U-87 MG cells. 5 ng/mL of rHuIL-31 can effectively induce STAT3 activation.
Manufacturer - Format
Lyophilized powder
Uniprot Entry Name
IL31_HUMAN
Protein Description
Full Length of Mature Protein
PubMed ID
15184896; 15489334; 16461143; 17030248

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2 ug
Available: In stock
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