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AES-350

AES-350

Item no.	DCC-AES-350-100mg
Manufacturer	DCChemicals
CASRN	847249-57-4
Amount	100 mg
Quantity options	100 mg 1 g 250 mg
Category	Reagents & Chemicals Building Blocks & Intermediates general
Type	Chemicals
Specific against	other
Smiles	CC(C1=CC=C(C(NC2=CC=C(C(NO)=O)C=C2)=O)C=C1)(C)C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Manufacturer - Applications	AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 is also against HDAC3, HDAC8 in an enzymatic activity assay with IC50 values of 0.187 μM and 0.245 μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
Molecular Weight	312, 363

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 10/23/2025

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