40824

Item no.	DCC-DC60825-100mg
Manufacturer	DCChemicals
Amount	100 mg
Quantity options	100 mg 25 mg 50 mg
Category	In Vivo
Applications	IV
Specific against	other
Purity	>95%
Smiles	O=C(CCCCCCC)OC(CCCCCCCC)CN(CCN1CCCC1)CC(CCCCCCCC)OC(CCCCCCC)=O
Available
Manufacturer - Applications	11-10-8 is an ionizable cationic lipid (pKa = 6.22) that has been used in the generation of lipid nanoparticles (LNPs) for mRNA delivery in vivo.1 LNPs containing 11-10-8 and encapsulating mRNA encoding the Cas9 nuclease and small-guide RNA (sgRNA) targeting transthyretin (TTR), a thyroid hormone carrier protein, decrease serum levels of TTR in mice. LNPs containing 11-10-8 and encapsulating mRNA encoding human fibroblast growth factor 21 (hFGF21) increase serum levels of hFGF21, decrease body and liver weights, and reduce the liver steatosis score in a mouse model of obesity induced by a high-fat diet.
Molecular Weight	679, 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Delivery expected until 1/22/2026

Express Delivery: Save 2 days

Compare

Add to wishlist

Get an offer