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Biotinylated Human DR3/TNFRSF25 Protein (DR3-HM401B)

Biotinylated Human DR3/TNFRSF25 Protein (DR3-HM401B)

Item no.	DR3-HM401B-100UG
Manufacturer	KactusBio
Amount	100 ug
Quantity options	100 ug 500 ug
Category	Cell Biology Cell Status Apoptosis
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	HIS, Avi
Purity	> 95% as determined by Bis-Tris PAGE
Dry ice	Yes
Sequence	Gln25-Gln199
NCBI	AAI17190.1
Alias	APO3,DDR3,DR3,TNFRSF12,WSL,WSL1,TNFRSF25,LARD,TR3,TRAMP,WSL-LR
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	DR3/TNFRSF25
Manufacturer - Conjugate / Tag	C-His-Avi
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 26.40 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Description	Recombinant Biotinylated Human DR3/TNFRSF25 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln25-Gln199.
Background	Death Receptor 3 (DR3), also known as TNFRSF25, TRAMP, LARD, or WSL-1, is a death-domain-containing TNF-family receptor that, like its closest paralog TNFR1, binds the adaptor molecule TRADD through its cytoplasmic death domain. TRADD recruitment endows DR3 with dual-signaling capability to activate NF−κB and MAP-kinase signaling or alternatively trigger caspase activation and programmed cell death.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Biotinylated	yes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

DR3-HM401B-100UG-datasheet.pdf

DR3-HM401B-100UG-safety-datasheet.pdf