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(KO Validated) PHD2/EGLN1 Polyclonal Antibody

(KO Validated) PHD2/EGLN1 Polyclonal Antibody

Item no.	E-AB-90883-120uL
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 200 uL 60 uL
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Alias	EGLN1, C1orf12, ECYT3, HALAH, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6
Shipping condition	Cool pack
Available
Manufacturer - Category	Polyclonal Antibody
Shipping Temperature	Biological Ice Packs
Storage Conditions	-20°C for 12 months
Background	The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
Concentration	1mg/mL
Buffer	PBS with 0.05% proclin300, 50% glycerol, pH 7.3.
Purification Method	Affinity purification
Clonality	Polyclonal
Immunogen	A synthetic peptide of human PHD2/EGLN1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 120 uL

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Delivery expected until 7/10/2025

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