TLR5 Polyclonal Antibody

TLR5

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

TLR5

Recombinant protein of human TLR5