CYP17A1 Polyclonal Antibody

CYP17A1

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

CYP17A1

Recombinant protein of human CYP17A1