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PTPN13 Polyclonal Antibody

PTPN13 Polyclonal Antibody

Item no.	E-AB-13236-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Adenocarcinoma Immunohistochemistry ELISA Enzymes Fatty Acid Synthesis Primary Antibodies By Organ Brain Cancer
Type	Antibody Polyclonal
Applications	IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	APO1/CD95 (Fas) associated phosphatase, DKFZp686J1497, FAP 1, FAP1, Fas associated phosphatase 1, Fas associated protein tyrosine phosphatase 1, HGNC:9646, hPTPE1, Phosphatase rip, PNP 1, PNP1, Protein tyrosine phosphatase 1 Fas associated, protein tyrosine phosphatase 1E, Protein tyrosine phosphatase non receptor type 13, Protein tyrosine phosphatase nonreceptor type 13, Protein tyrosine phosphatase PTPL1, protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase), PTP BAS, PTP BL, PTP E1, PTP1E, PTPL 1, PTPL1, PTPLE, PTPN 13, PTPN13, Tyrosine protein phosphatase non receptor type 13
Similar products	FAP1, protein tyrosine phosphatase, DKFZp686J1497, PNP1, PTP1E, PTPL1, PTPLE, protein tyrosine phosphatase 1E, PTPN13, Fas associated phosphatase 1, Protein tyrosine phosphatase non receptor type 13, PTP BAS, PTP BL, FAP 1, Fas associated protein tyrosine phosphatase 1, HGNC:9646, hPTPE1, PNP 1, Protein tyrosine phosphatase 1 Fas associated, Protein tyrosine phosphatase nonreceptor type 13, Protein tyrosine phosphatase PTPL1, PTP E1, PTPL 1, PTPN 13, Phosphatase rip, APO1/CD95 (Fas) associated phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase), Tyrosine protein phosphatase non receptor type 13
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	PTPN13
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	Cancer, Cell Biology, Signal Transduction
Background	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Concentration	0.5 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	IHC 1:25-1:100
Santa Cruz #	sc-1138, sc-1729, sc-15356
Abbreviation	PTPN13
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PTPN13
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.