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CERS4 Polyclonal Antibody

CERS4 Polyclonal Antibody

Item no.	E-AB-13375-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot ELISA Enzymes Prostaglandin Synthases Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ceramide synthase 4, CerS4, FLJ12089, LAG1 homolog ceramide synthase 4, LAG1 longevity assurance homolog 4, LAG1, S. cerevisiae, homolog of, 4, LASS 4, LASS4, LASS4 LAG1 homolog ceramide synthase 4, LASS4, TRAM homolog 1, Trh 1, Trh1
Similar products	LASS4, 4, S. cerevisiae, homolog of, LAG1, CerS4, FLJ12089, Trh1, LAG1 longevity assurance homolog 4, LAG1 homolog ceramide synthase 4, LASS 4, LASS4 LAG1 homolog ceramide synthase 4, Trh 1, ceramide synthase 4, TRAM homolog 1
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CERS4
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	46kDa
Research Areas	Cancer, Metabolism, Signal Transduction
Background	The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
Concentration	0.9 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:50-1:200
Santa Cruz #	sc-65112, sc-65113
Abbreviation	CERS4
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CERS4
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.